PVNS is an idiopathic neoplastic synovial diseases that is characterized by the overgrowth of synovium that eventually worsens and leads to bone damage and arthritis.
It is of two types :
Localized PVNS – tumor localized to one area of the joint
Diffuse PVNS – involves the entire joint and is difficult to treat
Exact etiology not known. It is diagnosed by x-rays, magnetic resonance imaging scan, joint aspiration and biopsy.
Symptoms :
Swelling and pain in the affected joint
Locking, catching and instability in the joint
Joint stiffness
Treatment includes surgical procedures like arthroscopy, open surgery, total knee replacement, radiation therapy and drugs that target Colony Stimulating Factor -1 Receptor protein.
Admin_NHT Staff asked 5 years ago