Thalassemia: Signs and Symptoms

Thalassemia is an inherited impairment of hemoglobin production. It is a blood disorder characterized by less hemoglobin and fewer red blood cells in the blood than normal.

Signs and Symptoms include:

• Weakness, fatigue, and malaise
• Pallor
• Deformities of facial bones
• Slow growth
• Urine is dark and concentrated
• Abdominal swelling
• Massive bone marrow expansion occurs which leads to the development of chipmunk facies in children, thinning and pathological fracture of long bones and vertebrae.

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